Cholecysitis

Specimen: Blood cultures

First line therapy:
CefUROXime 1.5g IV 8 hourly
AND
Metronidazole 500mg IV 8 hourly

If severe penicillin allergy
Ciprofloxacin 400mg IV 12 hourly
AND
Metronidazole 500mg IV 8 hourly

OR antibiotics according to blood culture isolate sensitivities.